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	<title>Comments on: Spermine (DNA Packing Material)</title>
	<link>http://www.moleculeoftheday.com/2006/06/15/spermine-dna-packing-material/</link>
	<description>Molecules: You'd Better Learn to Live With Them</description>
	<pubDate>Wed, 27 Aug 2008 23:58:41 +0000</pubDate>
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		<title>by: Jonathan Quince</title>
		<link>http://www.moleculeoftheday.com/2006/06/15/spermine-dna-packing-material/#comment-285</link>
		<pubDate>Tue, 27 Jun 2006 14:56:08 +0000</pubDate>
		<guid>http://www.moleculeoftheday.com/2006/06/15/spermine-dna-packing-material/#comment-285</guid>
					<description>The thrust of this comports with what I have found in my reading.  I also take it that spermine and spermidine are loads of olfactory fun in the lab.  Thanks for giving the public a chemist's penetrating insight in a lay-accessible explanation.  I shall most probably swallow the bait and blog this myself rather soon; looking ahead further, this area is fertile ground for research by a science-lover &lt;em&gt;cum&lt;/em&gt; sex-scholar such as I.

Analogously, I have also been looking to find information on the divers interesting compounds in vaginal fluid---particularly what gifts it with its physical, biochemical, and aromatic properties[*].    &lt;a href=&quot;http://en.wikipedia.org/wiki/Vaginal_lubrication&quot; title=&quot;Vaginal Lubrication - Wikipedia&quot; rel=&quot;nofollow&quot;&gt;Wikipedia yields the following list&lt;/a&gt;: &quot;water, pyridine, squalene, urea, acetic acid, lactic acid, complex alcohols and glycols, ketones, and aldehydes&quot;  Without further elaboration or appropriate citations, I take it with a crystal of sodium chloride.

Nonetheless, I'd really like to know what &quot;complex alcohols and glycols&quot; they are talking about, as those (along with squalene) are where I'd look first for the slippery magic.  Might the likes of glycerol or propylene glycol perhaps be involved?  IIRC, those are both ingredients in Astroglide (c.f. K-Y Jelly, which as &lt;a href=&quot;http://www.moleculeoftheday.com/2006/06/20/carboxymethylcellulose-ok-back-to-starch/&quot; title=&quot;Carboxymethylcellulose (OK, back to starch) - MOTD&quot; rel=&quot;nofollow&quot;&gt;you covered the other day&lt;/a&gt;, contains carboxymethylcellulose---probably glycerol too, from its taste).  As for pyridine, if that is correct, I hypothesize we have found the source of many puerile jokes.

I have also heard that vaginal secreta may contain compounds which interact with spermatozoa in interesting ways less obvious than the hydrogen activity effects mentioned above.  However, I shan't speculate before I hit the books and read up.  Search &quot;human sperm competition&quot; for details.

[*] Aromatic as in scent, &lt;em&gt;and&lt;/em&gt; aromatic in the benzene-chemistry sense, per pyridine and the like.  Sweet and sour!</description>
		<content:encoded><![CDATA[<p>The thrust of this comports with what I have found in my reading.  I also take it that spermine and spermidine are loads of olfactory fun in the lab.  Thanks for giving the public a chemist&#8217;s penetrating insight in a lay-accessible explanation.  I shall most probably swallow the bait and blog this myself rather soon; looking ahead further, this area is fertile ground for research by a science-lover <em>cum</em> sex-scholar such as I.</p>
<p>Analogously, I have also been looking to find information on the divers interesting compounds in vaginal fluid&#8212;particularly what gifts it with its physical, biochemical, and aromatic properties[*].    <a href="http://en.wikipedia.org/wiki/Vaginal_lubrication" title="Vaginal Lubrication - Wikipedia" rel="nofollow">Wikipedia yields the following list</a>: &#8220;water, pyridine, squalene, urea, acetic acid, lactic acid, complex alcohols and glycols, ketones, and aldehydes&#8221;  Without further elaboration or appropriate citations, I take it with a crystal of sodium chloride.</p>
<p>Nonetheless, I&#8217;d really like to know what &#8220;complex alcohols and glycols&#8221; they are talking about, as those (along with squalene) are where I&#8217;d look first for the slippery magic.  Might the likes of glycerol or propylene glycol perhaps be involved?  IIRC, those are both ingredients in Astroglide (c.f. K-Y Jelly, which as <a href="http://www.moleculeoftheday.com/2006/06/20/carboxymethylcellulose-ok-back-to-starch/" title="Carboxymethylcellulose (OK, back to starch) - MOTD" rel="nofollow">you covered the other day</a>, contains carboxymethylcellulose&#8212;probably glycerol too, from its taste).  As for pyridine, if that is correct, I hypothesize we have found the source of many puerile jokes.</p>
<p>I have also heard that vaginal secreta may contain compounds which interact with spermatozoa in interesting ways less obvious than the hydrogen activity effects mentioned above.  However, I shan&#8217;t speculate before I hit the books and read up.  Search &#8220;human sperm competition&#8221; for details.</p>
<p>[*] Aromatic as in scent, <em>and</em> aromatic in the benzene-chemistry sense, per pyridine and the like.  Sweet and sour!
</p>
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		<title>by: Jose Miguel</title>
		<link>http://www.moleculeoftheday.com/2006/06/15/spermine-dna-packing-material/#comment-185</link>
		<pubDate>Mon, 19 Jun 2006 02:26:09 +0000</pubDate>
		<guid>http://www.moleculeoftheday.com/2006/06/15/spermine-dna-packing-material/#comment-185</guid>
					<description>very interesting..</description>
		<content:encoded><![CDATA[<p>very interesting..
</p>
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		<title>by: Spermy McSemen</title>
		<link>http://www.moleculeoftheday.com/2006/06/15/spermine-dna-packing-material/#comment-149</link>
		<pubDate>Fri, 16 Jun 2006 02:38:17 +0000</pubDate>
		<guid>http://www.moleculeoftheday.com/2006/06/15/spermine-dna-packing-material/#comment-149</guid>
					<description>Hehehehe.   Sperm.

I'm not a biologist, but you've explained this in a way that I can understand.  Thanks :)</description>
		<content:encoded><![CDATA[<p>Hehehehe.   Sperm.</p>
<p>I&#8217;m not a biologist, but you&#8217;ve explained this in a way that I can understand.  Thanks <img src='http://www.moleculeoftheday.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' />
</p>
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